1. Alexander JW. History of the medical use of silver. Surg Infect (Larchmt). 2009, 10(3): 289-92. doi: 10.1089/sur.2008.9941.

2. Shcherbakov AB, Korchak GI, Surmasheva YeV, et al. Preparaty serebra: vchera, segodnya zavtra. Pharmaceutical Journal. 2006, 5: 45-57 (in Russian).

3. Flexner S, Amoss HL. Chemical versus serum treatment of epidemic meningitis. J Exp Med. 1916, 23(5):683-701. doi: 10.1084/jem.23.5.683.

4. Samtsov AV, Telichko IN, Statsenko AV & Khairutdinov VR. Application of external drugs comprising silver compounds for the treatment of pyodermic patients. Vestnik dermatologii i venerologii. 2014, 90(1): 75-80. doi: 10.25208/0042-4609-2014-90-1-75-80

5. Rybka M, Mazurek Ł, Konop M. Beneficial Effect of Wound Dressings Containing Silver and Silver Nanoparticles in Wound Healing-From Experimental Studies to Clinical Practice. Life (Basel). 2022, 13(1):69. doi: 10.3390/life13010069.

6. Shawcross J, Bakhai A, Ansaripour A, et al. In vivo biocompatibility and pacing function study of silver ion-based antimicrobial surface technology applied to cardiac pacemakers. Open Heart. 2017, 4(1):e000357. doi: 10.1136/openhrt-2015-000357.

7. Tagandurdyeva N, Yudin VE. Bioresorbable Composites for Bone Reconstruction. Nanotechnologies in Russia. 2020, 15(7-8): 400-414. 10.1134/S1995078020040151

8. Fernandez CC, Sokolonski AR, Fonseca MS, et al. Applications of Silver Nanoparticles in Dentistry: Advances and Technological Innovation. Int J Mol Sci. 2021, 22(5): 2485. doi: 10.3390/ijms22052485.

9. Rao MMV, Mohammad N, Banerjee Sh & Khanna PK. Synthesis and food packaging application of silver nano-particles: A review, Hybrid Advances, 2024, 6: 100230, https://doi.org/10.1016/j.hybadv.2024.100230.

10. Kapuścińska A, Nowak I. Silver nanoparticles as a challenge for modern cosmetology and pharmacology in ‘Nanobiomaterials in Galenic Formulations and Cosmetics’, Editor(s): Alexandru Mihai Grumezescu. William Andrew Publishing, 2016, 395-417pp., https://doi.org/10.1016/B978-0-323-42868-2.00015-2.

11. Jadhav SA, Patil AH, Thoravat SS, et al. A Brief Overview of Antimicrobial Nanotextiles Prepared by In Situ Synthesis and Deposition of Silver Nanoparticles on Cotton. Nanobiotechnology Reports. 2021, V. 16 (4): 543-550. doi: 10.1134/S2635167621040170

12. Khan S, Zahoor M, Khan RSh, et al. The impact of silver nanoparticles on the growth of plants: The agriculture applications. Heliyon. 2023, 9(6): e16928, https://doi.org/10.1016/j.heliyon.2023.e16928.

13. De Matteis V, Cascione M, Toma CC, & Leporatti S. Silver Nanoparticles: Synthetic Routes, In Vitro Toxicity and Theranostic Applications for Cancer Disease. Nanomaterials 2018, 8(5):319. https://doi.org/10.3390/nano8050319

14. Akter M, Sikder MT, Rahman MM, et al. A systematic review on silver nanoparticles-induced cytotoxicity: Physicochemical properties and perspectives. J Adv Res. 2017. 9:1-16. doi: 10.1016/j.jare.2017.10.008.

15. Noga M, Milan J, Frydrych A & Jurowski K. Toxicological Aspects, Safety Assessment, and Green Toxicology of Silver Nanoparticles (AgNPs)—Critical Review: State of the Art. International Journal of Molecular Sciences. 2023, 24(6):5133. https://doi.org/10.3390/ijms24065133

16. Kakakhel MA, Wu F, Sajjad W, et al. Long-term exposure to high-concentration silver nanoparticles induced toxicity, fatality, bioaccumulation, and histological alteration in fish (Cyprinus carpio). Environ Sci Eur 33, 14 (2021). https://doi.org/10.1186/s12302-021-00453-7

17. Ryan J, Jacob P, Lee A, et al. Biodistribution and toxicity of antimicrobial ionic silver (Ag+) and silver nanoparticle (AgNP+) species after oral exposure, in Sprague-Dawley rats, Food and Chemical Toxicology. 2022. 166: 113228, https://doi.org/10.1016/j.fct.2022.113228.

18. Zhang J, Liu S, Han J, et al. On the developmental toxicity of silver nanoparticles. Materials & Design, 2021. 203: 109611, https://doi.org/10.1016/j.matdes.2021.109611.

19. Antsiferova A, Kopaeva M, Kashkarov P. Effects of Prolonged Silver Nanoparticle Exposure on the Contextual Cognition and Behavior of Mammals. Materials. 2018. 11(4): 558. https://doi.org/10.3390/ma11040558

20. Węsierska M, Dziendzikowska K, Gromadzka-Ostrowska J, et al. Silver ions are responsible for memory impairment induced by oral administration of silver nanoparticles. Toxicol Lett. 2018. 290(133). doi: 10.1016/j.toxlet.2018.03.019.

21. Maciejewski R, Radzikowska-Büchner E, Flieger W, et al. An Overview of Essential Microelements and Common Metallic Nanoparticles and Their Effects on Male Fertility. Int. J. Environ. Res. Public Health. 2022. 19: 11066. https://doi.org/10.3390/ijerph191711066

22. Nosrati H, Hamzepoor M, Sohrabi M, et al. The potential renal toxicity of silver nanoparticles after repeated oral exposure and its underlying mechanisms. BMC Nephrol. 2021, 22(1): 228. doi: 10.1186/s12882-021-02428-5.

23. Belji Kangarlou M, Khavanin A, Nadri F, et al. Noise and silver nanoparticles induce hepatotoxicity via CYP450/NF-Kappa B 2 and p53 signaling pathways in a rat model. Toxicol Ind Health. 2024. 40(4): 206-219. doi: 10.1177/07482337241233317.

24. Buzulukov YuP, Arianova E., Demin VF, et al. Bioaccumulation of silver and gold nanoparticles in organs and tissues of rats studied by Neutron Activation Analysis. Biology Bulletin. 2014, 41(3): 255-263, doi: 10.1134/S1062359014030042.

25. Antsiferova, AA, Buzulukov YP, Demin VA, et al. Radiotracer methods and neutron activation analysis for the investigation of nanoparticlebiokinetics in living organisms. Nanotechnol. Russ. 2015, 10(1-2): 100–108, doi: 10.1134/S1995078015010024

26. Shipelin VA, Gmoshinski IV, Khotimchenko SA. Risk assessment of silver nanoparticles. IOP Conf. Series: Materials Science and Engineering. 2015, 98: 012010, doi:10.1088/1757-899X/98/1/012010

27. Uniform sanitary and epidemiological and hygienic requirements for products subject to sanitary and epidemiological supervision (control) accepted by Eurasian Economic Union. Available online: https://eec.eaeunion.org/comission/department/depsanmer/regulation/P2_299.php (Accessed on 08/02/2025).

28. Antsiferova AA, Kopaeva MY Comparison of silver nanoparticle’s and silver citrate neurotoxicity on the organisms of laboratory mammals. 2023. Medline.ru. 24: 819-828 (in Russian).

29. Antsiferova AA, Kopaeva MYu, Kashkarov PK. Relationships between Effects of Ag Nanoparticles and Ag Salt on Behavioral and Cognitive Functions of Mice and Ageing. Nanobiotechnology Reports. 2022. 17(6): 857–865. doi: 10.1134/S2635167622340018

30. Antsiferova AA, Kopaeva MYu, Kochkin VN. Neurotoxicity of Silver Nanoparticles and Non-Linear Development of Adaptive Homeostasis with Age. Micromachines, 2023, 14, 984. https://

31. doi.org/10.3390/mi14050984

32. Farimaneh J, Tabandeh MR, Fatemi Tabatabaei SR. Nasal Administration of Silver Nanoparticles and Silver Ions Reduced Cognitive Performance in Adult Rats. Universal Journal of Pharmaceutical Research 2023, 8(2):71-76, doi:10.22270/ujpr.v8i2.929

33. Sprando RL, Black T, Keltner Z, et al. Silver acetate exposure: Effects on reproduction and post natal development. Food Chem Toxicol. 2017, 106(Pt A):547-557. doi: 10.1016/j.fct.2016.06.022

34. Loeschner K, Hadrup N, Qvortrup K, et al. Distribution of silver in rats following 28 days of repeated oral exposure to silvernanoparticles or silver acetate. 2011. Part Fibre Toxicol. 1(8):18. doi: 10.1186/1743-8977-8-18.

35. Mertens J, Alami A, Arijs K. Comparative in vivo toxicokinetics of silver powder, nanosilver and soluble silver compounds after oral administration to rats. Arch Toxicol. 2023, 97(7):1859-1872. doi: 10.1007/s00204-023-03511-6

36. Dziendzikowska K, Węsierska M, Gromadzka-Ostrowska J, et al. Silver Nanoparticles Impair Cognitive Functions and Modify the Hippocampal Level of Neurotransmitters in a Coating-Dependent Manner. International Journal of Molecular Sciences. 2021, 22(23):12706. https://doi.org/10.3390/ijms222312706

37. Bilberg K, Hovgaard MB, Besenbacher F & Baatrup E. In Vivo Toxicity of Silver Nanoparticles and Silver Ions in Zebrafish (Danio rerio). J Toxicol. 2012, 2012:293784. doi: 10.1155/2012/293784.

38. Fu CW, Horng JL, Tong SK, et al. Exposure to silver impairs learning and social behaviors in adult zebrafish. J. Hazard.Mater. 2021. 403: 124031. https://doi.org/10.1016/j.jhazmat.2020.124031

39. Guo X, Li Y, Yan J, et al. Size- and coating-dependent cytotoxicity and genotoxicity of silver nanoparticles evaluated usingin vitrostandard assays. Nanotoxicology. 2016. 10(9): 1373–1384. doi:10.1080/17435390.2016.1214764

40. Vrček IV, Žuntar I, Petlevski R, et al. Comparison of in vitro toxicity of silver ions and silver nanoparticles on human hepatoma cells. Environ Toxicol. 2016, 31(6):679-92. doi: 10.1002/tox.22081.

41. Petritskaya EN, Rogatkin DA, Rusanova EV. Comparative characteristics of antibacterial effect of silver and nanosilver in vitro. Al’man. Klin. Med. 2016. 44: 221 (in Russian).

42. Nandhini J, Karthikeyan E, Elizabeth Rani E, et al. Advancing engineered approaches for sustainable wound regeneration and repair: Harnessing the potential of green synthesized silver nanoparticles. Engineered Regeneration, 2024, 5(3), 2024:306-325, https://doi.org/10.1016/j.engreg.2024.06.004.

43. Martin WJ, Benet Palmer S, Regenerative Wound Healing Using Copper-Silver Citrate Composition. Patent US 2010/0099758A1 from Apr. 22, 2010

44. Zhao S, Zhang J, Zhang J. Neuroprotective effects of biogenic silver nanoparticles in Parkinson's disease: In vitro and in vivo study. Int J Biol Macromol. 2024, 138236. doi: 10.1016/j.ijbiomac.2024.138236.

45. Scarpa E., Cascione M., Griego A., et al. Gold and silver nanoparticles in Alzheimer's and Parkinson's diagnostics and treatments. Ibrain. 2023, 9(3): 298. doi: 10.1002/ibra.12126.

46. Chountoulesi M, Demetzos C. Promising Nanotechnology Approaches in Treatment of Autoimmune Diseases of Central Nervous System. Brain Sci. 2020. 10(6):338. doi: 10.3390/brainsci10060338.

47. Antsiferova AA, Kashkarov PK. About therapeutic action of silver ions: A brief overview. Journal of Biological Regulators and Homeostatic Agents. 2025, 39(2): 3303. https://doi.org/10.54517/jbrha3303

48. Selye H. Stress without Distress. Progress Moscow; 1976, 126 p. (in Russian)