Assessment of genetic diversity in the Tuvan downy goat breed based on microsatellite DNA loci analysis

Yazilya Aminovna Khabibrakhmanova,Tatyana Borisovna Ganchenkova,Lyubov Aleksandrovna Kalashnikova,Raisa Shuguurovna Irgit,Mariya Ivanovna Dongak,Sayana Darzhaaevna Mongush,Sayana Khuragandaevna Bicheool,Buyan Mikhaylovich Mongush

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Assessment of genetic diversity in the Tuvan downy goat breed based on microsatellite DNA loci analysis

Ya. A. Khabibrakhmanova,

T. B. Ganchenkova,

L. A. Kalashnikova,

R. Sh. Irgit,

M. I. Dongak,

S. D. Mongush,

S. K. Bicheool,

B. M. Mongush

2025-11-18

https://doi.org/10.24108/preprints-3113914

The study aims to assess the genetic diversity of the Tuvan cashmere goat breed, patented and registered in the State Register of Protected Breeds of the Russian Federation in 2024. The study was conducted using 14 microsatellite loci recommended by the International Society of Animal Genetics (ISAG). Microsatellite markers remain an important tool in population genetics due to their high polymorphism, reproducibility, and low cost. Their use in animal breeding covers tasks ranging from gene pool conservation to identifying links with economically valuable traits. The Tuvan cashmere goat breed is a unique genetic resource of Siberia, adapted to extreme climatic conditions. The wool of goats of this breed is distinguished by a high content (82–91%) of fine (16–18 µm) down fibers. Genetic studies of this new breed remain limited, making this research relevant. The study was conducted on a sample of 337 animals selected in the Republic of Tuva. A high genetic diversity of the population was established: the total number of alleles was 104, the average number of alleles per locus was 7.43. The most polymorphic loci were SRCRSP23 (11 alleles), MAF065 and SRCRSP5 (10 alleles each). The values of observed and expected heterozygosity were 0.722 and 0.715, respectively. The inbreeding coefficient (Fis = -0.010) indicates the absence of inbreeding depression in the studied population. The obtained results characterize the Tuvan cashmere goat breed as a valuable genetic resource with a high level of genetic diversity and a stable population structure. The identified highly polymorphic markers are recommended for use in breed genetic monitoring programs and selection programs.

Ссылка для цитирования:

Khabibrakhmanova Ya. A., Ganchenkova T. B., Kalashnikova L. A., Irgit R. Sh., Dongak M. I., Mongush S. D., Bicheool S. K., Mongush B. M. 2025. Assessment of genetic diversity in the Tuvan downy goat breed based on microsatellite DNA loci analysis. PREPRINTS.RU. https://doi.org/10.24108/preprints-3113914

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